An India-born Nobel laureate’s solutions for fixing science in India by Akshat Rathi

Venkataraman Ramakrishnan is a biologist—even though he won the Nobel Prize in chemistry 2009—and an Indian at heart, even though he has spent most of life in the US and the UK where his work led to the prize. His career has been unusual, just as his achievements.

Born to scientist parents in Tamil Nadu, Venki grew up in Gujarat. There his parents helped setup the biochemistry department at the Maharaj Sayajirao University of Baroda. The nerdish Venki paced through school and an undergraduate degree in physics, before moving to the US to pursue a PhD in physics at the age of 19.

On reading articles in the Scientific American about breakthroughs in biology, he was hooked and switched fields to pursue a career in biology where his knowledge of physics would prove crucial. But he wouldn’t have earned the Nobel Prize, which was given for his work on the structure of ribosome, had he not taken a sabbatical at the age of 40 to studied the chemist’s tool of crystallography to peer at the molecular structure of chemicals.[pullquote]He will be the first non-white President of the 350-year-old Royal Society.[/pullquote]

In December, he is going to take his new position as the President of the Royal Society, the world’s oldest and most esteemed scientific society. He will be the first non-white president in its 350-year history, and he has already made plans to invigorate scientific ties between India and the UK.

We met Venki at this year’s Lindau Nobel Laureates Meeting held in Bavaria, Germany. He comes across as scholarly and soft-spoken, yet frank and forthright. In a conversation with Akshat Rathi of Quartz and Harini Barath of India Biosciences, he talks about fixing science in India, difficulties of a career in science, and some lighter subjects. The interview has been condensed and lightly edited for clarity.

Akshat and Harini: What is your opinion of the level of scientific research in India?

Venki: The institutes I have visited are the cream of the crop. So my view of Indian science is obviously skewed by that. But, if you go to your typical state university, and I’ve done that also, then you find that they have very poor infrastructure, very poor funding, and a rather low level of research, usually very incremental.[pullquote]I worry about the breadth of the Indian scientific enterprise. [/pullquote]

I worry about the breadth of the Indian scientific enterprise. I think there’s not enough investment in training people properly. There’s a divorce between research and education, by putting research in central institutes and leaving universities to fend for themselves.

How do you think things can be improved?

The government is trying to restore things by creating the Indian Institutes for Science Education and Research (IISERs). I’ve visited two IISERs and I was impressed by both of them.

Taking on the hard problems.

Taking on the hard problems.

But, of course, you need many more high level institutions for a country of a billion people. State universities need to have better faculty who know what good research is. Otherwise undergraduates as a whole are not going to be exposed to very good science. And that takes a lot of investment.

If you look at the difference in investment between India and China, for instance, it’s a stark difference even when you correct for the fact that China has a bigger economy. When I go to China, I see a country that, in some ways, has caught up with the West; perhaps not with the very best of the West, but certainly with the average. I don’t see that in India, except for very few elite institutions.

So funding is one way to solve the problem, and the other way is to balance research and education in institutions.

Yes. Britain is a real example in this regard. It balances between research institutes (like the MRC Lab where I work) and some very well funded university programs. I think you need both, because the two can do different kinds of science. For instance, we can engage in long-term science, and often universities, with their turnover of students and so on cannot always do that. And I think they’re complementary. It’s the kind of scientific infrastructure that a country like India needs to create.

To promote universities, you have to attract talent. How can you get a young scientist to take that leap and become a faculty member at a place with possibly low funding?

So the only way you can do that is by jumpstarting a place. And state governments can help with this. They can provide matching funds, or even a majority of the funds. They can say, we want to make this university in our state a center of excellence in this particular area. We’re going to put a lot of money into it and attract this one senior person who is known to be very good to help recruit younger scientists.

65th Lindau Nobel Laureate Meeting

A good listener.

This leads to another problem. Senior scientists need to know when to step down gracefully. And their goal should be to promote people who’ll take over from them. There are very few Institutions in India that do this.

In my job as head of division at the MRC Lab of Molecular Biology for the last 10 years, we have done a lot of recruiting. Whenever I recruit, the question I ask is “Is this person likely to replace me one day?” And if the answer is yes, that’s the sort of person I want. And we do everything possible to make sure their careers flourish.

This is a good excuse to talk about your next position at the Royal Society. What legacy would you like to leave?

It’s a little premature to ask me because I don’t take up office until December, but I have a few ideas. One is to increase support for science from the government, and to increase public awareness and interest in science. Another thing is to work with other organizations to help raise the standards of education, especially in schools, of science. Another thing is to make sure that whenever there are difficult issues, the Royal Society engages productively in getting the best expert opinion on these issues, and producing good policy statements both for Government and the public.[pullquote]Senior scientists in India need to know when to step down gracefully.[/pullquote]

Of course, another aspect in which I am interested, as somebody who was born in India, is to engage with other countries, especially to foster exchange and collaborations. One idea is to try and get support for exchange programs between Indian scientists and students and British institutions. I think that would be great.

You met your wife when she was studying painting? Does having a non-science person as your partner help in any way?

I can say there are advantages and disadvantages. The advantage is that when I get home, I don’t have to talk about science, and I can talk about all sorts of other things. So that’s very refreshing. The disadvantage, of course, is that she doesn’t necessarily understand all of the problems and stresses I have, which are specific to science. I don’t think it matters one way or another. Two people just have to get along.

Onto some light-hearted questions. How much sleep do you need and does it affect your work?

I usually go to bed about 10pm or so. I wake up between 6am and 7am. I don’t function very well without a good night’s sleep.

Venki and Jack Szostak with Akshat and Harini.

Venki and Jack Szostak with Akshat and Harini.

Are you addicted to something? 

I’m addicted to surfing news articles on the internet. That’s a very bad addiction, because most of the things I read are not very lasting. If I hadn’t read them, there would be no consequence whatsoever. But the internet has this addictive quality, and it’s one thing I’m trying to control.

What’s your idea of a perfect holiday?

A perfect holiday would be either going on a hike or a bicycle ride, where I’m doing things outdoors and not thinking about all the stresses of life. Definitely away from email and work-related things.

Where do your best ideas come from?

Often they come when I’m engaged in some leisure activity. For instance, I’m on a walk or a bike, and suddenly, without actually realizing it, I’m thinking about some problem that’s been bothering me. In these moments, a new approach might occur to me. Occasionally, good ideas will come from reading something I wasn’t expecting to read. And very occasionally, they come from talking to people I meet, who may not be in my field but have an insight into my work that hadn’t occurred to me because the person’s an outsider.

What one advice would you give to young scientists?

Do something where you really care about the answer, because fads in science don’t last and the process of science can often be very tedious. You have to really care about the question and know the importance of finding the answer. That’s the most important thing, because that’s what will keep you interested and motivated.


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